Animal Health Professionals

Animal Health Professionals

(800) 944-7563





Totally Naked Mutant Core that doesn’t have the ability to grow Lipopolysaccharides (LPS). The core has a completely exposed cell wall that is common to all gram-negative bacteria.


Separate component, that is completely different than the bacterin. It is not just a loose toxin that has separated from the bacterin. It has been totally detoxified yet retains its mitogen properties through stimulation of certain Toll-Like Receptors (TLR). This makes it more than just an adjuvant and a true immunostimulant.

Two Technologies in One Bottle

Endovac Vaccine

Unprecedented efficacy

Doesn’t create large milk drop
due to no active endotoxins

Unrivaled pathogens protected

Immune Plus

Activated immune system for stronger responses

Only immune stimulant included in a vaccine

Increases antibodies, lymphocytes and neutrophils

Endovac Vaccine

Core Antigen common to all gram-negative bacteria

Safe and effective without negative active endotoxins

Broad Spectrum protection

ENDOVAC-Porci Bottle

Immune Plus

Activated immune system for stronger responses

Only immunostimulant to be inclueded in a swine vaccine

Easy to use, no mixing, low 1mL dose

Immune Plus®

Immune Plus is an Immunostimulant made from proprietary ENDOVAC Animal Health Technology. Immune Plus raises the overall response of the immune system in the animal. This is important both for response to vaccination as well overall health at critical times. As the graphs demonstrate, two key components of the immune system, lymphocytes and antibodies, are both significantly increased with Immune Plus. Elevating the animal’s own immune response to ward off harmful pathogens, as well as enhancing the response to all administered vaccinations, are key roles of Immune Plus.

Broad Spectrum of Protection

The way most vaccines are built, multiple antigens have to be added to the vaccine to get protection from multiple diseases. This cocktail method means that the animal has to respond to lots of different antigens individually. ENDOVAC-Porci® vaccine is different for two reasons. First, the way our core technology is built, it is broad spectrum with only one antigen – see diagram. Our unique antigen is the core of all gram-negative bacteria. This allows it to protect against multiple gram-negative bacterial diseases. Second, ENDOVAC-Porci is the only gram-negative vaccine to not have harmful active endotoxins. Endotoxins, also known as LPS, are not grown at all by our core antigen. This includes the toxin Lipid A, that plagues other gram-negative vaccines.

Antibody Titer LOG2 Chart
Lymphocytes Chart